产品货号:
Z25203
中文名称:
RIPK2抗体
英文名称:
Anti-RIPK2 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-RIPK2 Antibody |
指标别名 | CARD3;CARDIAK;CCK;GIG30;Receptor interacting protein 2;RICK;RIP 2;RIP2;RIPK2 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | WB,IHC,ELISA |
基因名称 | RIPK2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human RIP2 around the non-phosphorylation site of S176. |
计算分子量 | 61KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | RIPK2(Receptor-interacting serine/threonine-protein kinase 2),also known as CARD3,CARDIAK,RICK,RIP2,is an?enzyme?that in humans is encoded by the?RIPK2?gene.?It has 540-amino acid protein in length.?Northern blot analysis revealed that RICK is expressed in various human tissues as 2.5- and 1.8-kb mRNAs that differ due to alternative polyadenylation.RICK is a novel kinase that may regulate apoptosis induced by the FAS receptor pathway.This gene encodes a member of the receptor-interacting protein(RIP) family of serine/threonine protein kinases.The encoded protein contains a C-terminal?caspase recruitment domain(CARD),and is a component of signaling complexes in both the innate and adaptive immune pathways.It is a potent activator of?NF-kappa B?and inducer of apoptosis in response to various stimuli,CARDIAK(CARD-containing ICE-associated kinase) specifically interacted with the CARD of ICE/caspase-1,and this interaction correlated with the processing of pro-caspase-1 and the formation of the active caspase-1 p20 subunit. |
Uniprot ID | O43353 |
基因名全称 | Receptor-interacting serine/threonine-protein kinase 2 |
蛋白名全称 | Receptor-interacting serine/threonine-protein kinase 2 |
推荐稀释比 | WB 1:500~1:2000 IHC 1:100~1:300 ELISA 1:40000 |
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